Amputation Alternative Treatments For Dog Bone Cancer: Belle’s Journey Even though amputation is the treatment of choice of osteosarcoma and the majority of dogs adapt well and their owners are satisfied after surgery, it is not the right option for every dog and every family. In this video, we meet Belle who had a surgical limb spare procedure to remove the osteosarcoma, allowing her to keep her limb. Today is her final chemotherapy treatment, or chemotherapy graduation day as Dr Sue calls it.